Porous Silicon as Drug Delivery System
Abstract
Nanostructured silicon offers a high surface area, controllable pore size and convenient surface chemistry that make it a suitable material for several applications. Recently silicon nanostructures are actively investigated because of their biocompatibility and the possibility to fabricate fluorescent drug delivery carriers. To obtain vehicles with different release kinetics it is possible to relay on the different porous silicon morphologies, but also the LBL technique can be used. Moreover the porous particles can be coupled with thiolated polymers and the disulfide exchange reactions can be exploited to dynamically modulate the carriers properties.